Paul Offit

American immunologist

Paul Allan Offit (born 27 March 1951) is an American pediatrician specializing in infectious diseases, vaccines, immunology, and virology. He is the co-inventor of a rotavirus vaccine. Offit is the Maurice R. Hilleman Professor of Vaccinology, professor of pediatrics at the Perelman School of Medicine at the University of Pennsylvania, former chief of the Division of Infectious Diseases (1992–2014), and the director of the Vaccine Education Center at The Children's Hospital of Philadelphia.

Paul Offit


  • The hardest thing about making a vaccine is mass-producing it. You have to have the right buffering agent, the right stabilizing agent. You have to have the right vial. You have to do real-time stability studies to make sure that when the vaccine leaves the manufacturing plant, that the time it takes to get from the tarmac to the person's arm does not cause any problems. Because, remember, when you're shipping vaccines, they're going to be exposed to high temperatures and low temperatures, and you have to make sure that you have a stable product.

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