COVID-19 vaccine

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A COVID-19 vaccine is a hypothetical vaccine against coronavirus disease 2019 (COVID‑19). Although no vaccine has completed clinical trials, there are multiple efforts in progress to develop such a vaccine.

The only way to definitively eradicate the pandemic is to have a vaccine that can be administered to all inhabitants of the planet... To ensure the availability of the vaccines to all people on the planet almost at the same time, it has to be free from ownership. To do so we intend to make a global pharmaceutical social business operational as soon as possible. ~ Muhammad Yunus


(alpha by author)

  • We have people around the world working as fast as they can to try to develop an effective vaccine against this dangerous disease. That is great — except these people are working in competition, not in collaboration. They all want to be the first to develop a patentable vaccine that will allow them to get very rich if it proves successful... the coronavirus should be yet another lesson as to why there is a better alternative to patent monopolies for financing biomedical research.
A cooperative approach to developing vaccines is important because developing vaccines is an inherently risky undertaking... Only about 7 percent of vaccines in the early stages of development are successful, and only 17 percent of those that reach trials on humans end up being successful, according to figures compiled by GAVI, the Vaccine Alliance.
This devastating pandemic, with all its worldwide chaos and horror, has at the same time created a perfect alignment of technology, science, need, and opportunity. The global impact of Covid-19 could change science forever...Let’s Not Waste It, Jane Metcalfe
In case anyone is wondering I strongly support the development and widespread adoption of a covid-19 vaccine and will take it as soon as it is widely available... ~Jimmy Wales
  • Within days of the first confirmed novel coronavirus case in the United States on 20 January, antivaccine activists were already hinting on Twitter that the virus was a scam—part of a plot to profit from an eventual vaccine... Recent polls have found as few as 50% of people in the United States are committed to receiving a vaccine, with another quarter wavering... In France, 26% said they wouldn’t get a coronavirus vaccine... Even before the pandemic, public health agencies around the world were struggling to counter increasingly sophisticated efforts to turn people against vaccines. With vaccination rates against measles and other infectious diseases falling in some locations, the World Health Organization (WHO) in 2019 listed “vaccine hesitancy” as one of 10 major global health threats.
  • The race for a COVID-19 vaccine is setting off a different kind of competition in Washington: Who will get it first?... Trump administration officials have signaled they will take a “tiered approach” to giving out the vaccine when it is ready and said that, depending on the results of clinical trials, high-risk individuals, people with pre-existing health conditions, and front-line health care workers will be prioritized. After those groups, it’s anyone’s guess. “Will it be people at highest risk? Will it be people who are key to spreading and transmission? Will it be politically effective lobby groups? Will it be people who can pay the most for it?” said Barry Bloom, a research professor at the Harvard T.H. Chan School of Public Health.
  • The United States has bought up virtually all stocks of a drug shown to reduce the recovery time of COVID-19 patients... Remdesivir – an anti-viral drug first developed to tackle Ebola – has been approved for use treating coronavirus in the UK and the US after trials suggested it could cut recovery time by around four days... it will charge $2,340 (£1,900) for a typical treatment course for people in the U.S. and other developed countries... Critics in the U.S. attacked the price because taxpayers have funded much of the drug’s development.
  • It does raise two very important questions: what is a fair price for a drug, and what is fair access to a drug, and those are common issues but are particularly important in a global crisis like this. That’s part of the fair access question ― the trial that gave the result that allowed Remdesivir to sell their drug wasn’t just done in the U.S. There were patients participating through other European countries, in the U.K. as well, and internationally ― Mexico and other places... And I wonder how they would feel knowing now that the drug is going to have restricted availability in their own country and would they have volunteered for that trial if they had known that?
  • The details of the contracts come just days after the Trump administration faced backlash from consumer groups for refusing to require Gilead to charge a reasonable price for its Covid-19 treatment remdesivir. On Monday, as Common Dreams reported, Gilead announced it will charge U.S. hospitals around $3,120 per privately insured patient for a treatment course of remdesivir, which was developed with the help of at least $70.5 million in taxpayer funding. "Allowing Gilead to set the terms during a pandemic represents a colossal failure of leadership by the Trump administration," Peter Maybarduk, director of Public Citizen's Access to Medicines Program, said in a statement Monday. "The U.S. government has authority and a responsibility to steward the technology it helped develop."
  • If everything moves smoothly, it takes 3-6 weeks to get to the point where you can start testing (the vaccine to treat SARS-CoV-2), then you look to see if they can raise an immune response, normally in an animal. You won't start to get human studies until about the beginning of the summer, probably July (2020). But, it's a bit of a moveable feast.
  • Polls show that the American people are extremely worried about contracting the virus. However, the government has a much bigger concern: that if they find a COVID-19 vaccine, China will copy it and distribute it for free. To many, it will not be immediately clear why it would be a problem for a manufacturing superpower, home to 1.4 billion people, to inoculate itself and others. But to the White House, this would be “stealing” a potential American innovation.
  • In the early 1950s, American scientist Jonas Salk pioneered a world-changing vaccine against polio, a deadly disease that tens of thousands of Americans contracted annually. Instead of patenting it and making a fortune, he insisted that his invention belonged to all of humanity. By 1994, polio was eradicated in North America. Yet 70 years later, the logic of capitalism dictates that where... there are enormous profits to be made, and anyone acting outside that system to reproduce a vaccine is not acting responsibly, but “stealing.”
  • Today we envision a vaccine within two years, and for frontline health care workers, probably much sooner. It’s remarkable how fast science can happen when everyone is focused on the same problem. This devastating pandemic, with all its worldwide chaos and horror, has at the same time created a perfect alignment of technology, science, need, and opportunity. The global impact of Covid-19 could change science forever.
  • This vaccine will be needed by 8 billion people. What happens to poor countries who cannot afford to pay the prices that they'll be charging in the rich countries? Happy to sign, pledge your support
  • In case anyone is wondering I strongly support the development and widespread adoption of a covid-19 vaccine and will take it as soon as it is widely available... I don't think I should be in the first wave to take it as that should be people more vulnerable or more likely to be spreaders... I think that's right. [replying to comment: "it should go to health care workers first"]. I'm not an expert. I just know that I'm healthy and safe at home, so it will be more helpful for others to go first. But I'm eager to take it!
  • The long-term evidence of safety is going to be limited because these vaccines are going to have only 6 months or 5 months of data. So, we’re working super hard on a very active pharmacovigilance system, to make sure that when the vaccines are introduced that we’ll absolutely continue to assess their safety.
  • The problem is that whenever an immunologist says anything about Covid immunity to a journalist, it’s right for about two weeks and then it’s completely wrong.

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