Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB). Tuberculosis generally affects the lungs, but can also affect other parts of the body. The classic symptoms of active TB are a chronic cough with blood-containing sputum, fever, night sweats, and weight loss.
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- Tuberculosis is one of the classical afflictions of city life associated with poverty, overcrowding, malnutrition, and industrial stress. It often occurs when there is transition from a rural to urban life.
- During the period 1960–1980, with lower incidences and decreasing trends, TB ceased to be pursued actively as a research subject in several western countries. However, it continued to be a focus of research in developing countries, especially in India, where TB was and continues to be a major health burden. The late Prof. M. Sirsi is acknowledged to have initiated TB research at the Indian Institute of Science, Bangalore, one of the premier institutions of India.