- There's only one legend. That's me.
- Getting hit motivates me. It makes me punish the guy more. A fighter takes a punch, hits back with three punches.
- I am not an animal in my personal life. But in the ring there is an animal inside me. Sometimes it roars when the first bell rights. Sometimes it springs out later in a fight. But i can always feel it there, driving me and pushing me forward. It is what makes me win. It makes me enjoy fighting.
- My experience won this fight…. I knew I was in control. I was not scared. He was not hitting me with anything that was hurting me.
- I realized that my body can give me so much more.
- At lightweight it seemed he was a tremendous puncher, but I didn't find him to be that kind of puncher. A good puncher, a strong puncher, but not a devastating puncher.
- One gets the impression of Duran is that he’s a tough, rough brawler who just wades in and ducks nothing. But all you have to do is look at his face to see that is nonsense. He’s not marked up. He does a lot of cute things in there.
- Moving fluidly and jabbing, slipping punches and countering rather than swarming over DeJesus, he stalked him, relentlessly wearing him down and coolly destroying him with savage punches to the body. For 11 rounds Duran bested the classic boxer at his own game, robbing him of his speed and his will to fight, and only then did he permit himself the luxury of putting DeJesus away.
- He’s good inside, very good, strong physically. The one thing that surprised me the most was his quickness. And his defensive ability. He moves his head a lot, feints a lot. He’s not an easy man to hit.
- Duran knew how to fight. He knew what to do. If he looked at the corner the only thing I ever had to do was pretend to jab, once he was using his jab I knew he’d have no trouble. Even more important he knew how to think. When you talk about great fighters, always remember there was a guy named Roberto Duran. He was never given the opportunity to really display his wares because at his peak, he was overshadowed by Muhammad Ali.
- Ray Arcel, Duran's trainer 
- Duran has always been the master of defense that is one of his trademarks.
- Duran laid back, counterpunching,he's a three-time champion, a very gutsy warrior. I couldn't go in there and get foolish.
- That name, "Manos de Piedra", is true, Hands of Stone. Every punch, and I'm not exaggerating, every punch that he hit me with, from the body to the head, felt like bricks, stone, rocks. He knocked my teeth back. My front, my first 3 or 4 teeth, he knocked them back because he was just so possessed. He was a demon.
- ¡No más, no más!
- English: No more, no more!
- Infamous words supposedly uttered in quitting the Leonard-Duran II fight, which became known as the "No Más Fight"
- Kiger, Fred W. (19 November, 2003). "Duran wanted 'no mas' of Leonard". ESPN Classic (espn.go.com). Retrieved on 2007-08-06.
- "Roberto Duran: I never said 'No Mas'". EastSideBoxing.com. 17 June 2005. Retrieved on 2007-08-06.