Michaelis–Menten kinetics

Model of enzyme kinetics

In biochemistry, Michaelis–Menten kinetics is one of the best-known models of enzyme kinetics. It is named after German biochemist Leonor Michaelis and Canadian physician Maud Menten. The model takes the form of an equation describing the rate of enzymatic reactions, by relating reaction rate (rate of formation of product, ) to , the concentration of a substrate S.


    This is Michaelis and Menten's [1913] equation, (k2 + k3)/k1 representing their constant Ks. […] It may be remarked that with this modification of their theory, Michaelis and Menten's analysis of the effects of the products of the reaction, or other substances which combine with the enzyme, still holds good.

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