Michael Lai

Taiwanese virologist (born 1942)

Michael Lai (賴明詔; Lài Míngzhào; born 8 September 1942) is a Taiwanese virologist and distinguished research fellow at the Institute of Molecular Biology of Academia Sinica.


  • Coronaviruses include a group of RNA viruses of medical and veterinary importance, all of which are characterized by spherical, enveloped virus particles with prominent surface projections, resembling the corona of the sun. They infect various animal species, causing respiratory, gastrointestinal, cardiovascular, and neurological diseases. In humans, coronaviruses have been associated with common colds, diarrhea, and possibly multiple sclero­sis. The prototypical coronaviruses include avian infectious bronchitis virus (!BV), mouse hepatitis virus (MHV), porcine transmissible gastroenteritis virus (TGEV), bovine coronavirus (BCV), human coronavirus (HCV), feline infectious peritonitis virus (FIPV), rat sialodacryoadenitis virus (SDAV), turkey coronavirus (TCV), rabbit coronavirus (RCV), and several viruses of other animal species.
  • Hepatitis delta virus (HDV) contains a circular, viroid-like RNA genome, the only animal viral RNA of its kind. It possesses a ribozyme activity, which can autocatalytically cleave and ligate itself. The ribozyme has a unique structural requirement different from other known ribozymes.
Wikipedia has an article about: